Alcohols and polyols

Organic compounds containing one or more hydroxyl functional groups bonded to a carbon atom; hydroxyls consist of an oxygen atom bonded to a hydrogen atom. Alcohols exist in chain, or as closed rings. Polyols contain two or more hydroxyl groups.

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4,921 – 4,935 of 5,342 results

4,921

Medchemexpress LLC Pociredir hydrochloride | 2490676-19-0 | 99.9% | 439.87 | 5 MG

Pociredir hydrochloride (FTX-6058) is a potent and orally active inhibitor of Embryonic Ectoderm Development (EED). It can induce HbF protein expression in cell and murine models, making it suitable for research into select hemoglobinopathies, including sickle cell disease and β-thalassemia. It inhibits PRC2 by binding to EED, which leads to robust HbF protein expression.

Potent and orally active EED inhibitor
Induces HbF protein expression in cell and murine models
Useful for research on sickle cell disease and β-thalassemia
Inhibits PRC2 by binding to EED

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4,922

Medchemexpress LLC IACS-9571 hydrochloride | 2319611-93-1 | 98.3% | 679.22 | 1 MG

IACS-9571 hydrochloride (ASIS-P040) is a potent and selective inhibitor of TRIM24 and BRPF1. It shows excellent cellular potency with EC50 of 50 nM and potent activities against a panel of 32 bromodomains. It is also highly selective against BRPF2 and BRPF3, and does not interact with the BET sub-family of bromodomains.

Potent and selective TRIM24 and BRPF1 inhibitor
Excellent cellular potency (EC50 of 50 nM)
Potent activities against 32 bromodomains
High selectivity against BRPF2 and BRPF3
No interaction with BET sub-family bromodomains

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4,923

Medchemexpress LLC Emixustat hydrochloride | 1141934-97-5 | 99.29% | 299.84 | 5 MG

Emixustat hydrochloride is an orally active RPE65 inhibitor with an IC50 value of 4.4 nM. It is also a visual cycle modulator, capable of regulating visual cycle activity by inhibiting retinol isomerization, and holds potential for studying vision disorders such as age-related macular degeneration (AMD).

Orally active RPE65 inhibitor
IC50 value of 4.4 nM
Visual cycle modulator
Inhibits retinol isomerization
Regulates visual cycle activity
Investigated for potential in studying vision disorders such as age-related macular degeneration (AMD)

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4,924

Medchemexpress LLC SCH-23390 hydrochloride | 125941-87-9 | 99.8% | 324.24 | 1 ML

SCH-23390 hydrochloride is a potent and selective dopamine D1-like receptor antagonist with Kis of 0.2 nM and 0.3 nM for the D1 and D5 receptor, respectively. It is also a potent and high efficacy human 5-HT2C receptor agonist with a Ki of 9.3 nM, and binds with high affinity to 5-HT2 and 5-HT1C receptors. It inhibits G protein-coupled inwardly rectifying potassium (GIRK) channels with an IC50 of 268 nM. For research use only.

Potent and selective dopamine D1-like receptor antagonist.
Potent and high efficacy human 5-HT2C receptor agonist.
Binds with high affinity to 5-HT2 and 5-HT1C receptors.
Inhibits G protein-coupled inwardly rectifying potassium (GIRK) channels.
Used in studies of neurological disorders like psychosis and Parkinson's disease.
Used in topographical determination of brain D1 receptors.

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4,925

Medchemexpress LLC VU0453379 (hydrochloride) | 99.0% | 471.03 | 10 MG

VU0453379 hydrochloride is a highly selective and central nervous system (CNS) penetrant positive allosteric modulator (PAM) of glucagon-like peptide-1R (GLP-1R) with an EC50 of 1.3 μM.

Highly selective
Central nervous system (CNS) penetrant
Positive allosteric modulator (PAM) of glucagon-like peptide-1R (GLP-1R)

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4,926

Medchemexpress LLC Ru-ski 43 hydrochloride | 1782573-67-4 | 98.8% | 423.01 | 50 MG

RU-SKI 43 hydrochloride is a potent and selective Hedgehog acyltransferase (Hhat) inhibitor with an IC50 of 850 nM. It reduces Gli-1 activation through Smoothened-independent non-canonical signaling and decreases Akt and mTOR pathway activity. It also exhibits anti-cancer activity.

Potent and selective Hhat inhibitor (IC50 = 850 nM).
Reduces Gli-1 activation via Smoothened-independent non-canonical signaling.
Decreases Akt and mTOR pathway activity.
Possesses anti-cancer activity.

Pricing & Availability

4,927

Medchemexpress LLC 4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide hydrochloride | 2115897-23-7 | MFCD32062443 | 99.2% | 467.02 | C22H31ClN4O3S | 10MG

(S,S,S)-AHPC hydrochloride is a research-grade VHL ligand provided as the hydrochloride salt. It is used as a building block or negative control in protein degrader (PROTAC) development and biochemical studies of von Hippel-Lindau (VHL) E3 ligase recruitment.

Research-grade VHL ligand for protein degrader and binding studies.
High purity suitable for biochemical and cell-based assays (99.2%).
Hydrochloride salt form to enhance solubility in polar solvents.
Molecular weight 467.02 and formula C22H31ClN4O3S.
Supplied as a 10 mg vial for small-scale research use.

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4,928

Medchemexpress LLC Yonkenafil hydrochloride | 804519-64-0 | 99.4% | 524.08 g/mol | C24H34ClN5O4S | 50MG

Yonkenafil hydrochloride is a research-grade phosphodiesterase 5 (PDE5) inhibitor supplied as the hydrochloride salt for laboratory pharmacology studies. It has demonstrated neuroprotective and cognitive effects in preclinical models and is suitable for both in vitro assays and in vivo formulations. This material is intended for research use only and should be handled and stored to minimize moisture exposure.

Purity 99.4%.
Molecular weight 524.08 g/mol.
Chemical formula C24H34ClN5O4S.
Soluble in DMSO at 100 mg/mL with sonication.
Formulatable for in vivo dosing at ≥2.5 mg/mL in recommended vehicles.
Store sealed and protected from moisture and light; freeze solutions for longer-term storage.

Pricing & Availability

4,929

Medchemexpress LLC Amotosalen hydrochloride | 161262-45-9 | MFCD09970539 | 99.9% | 337.8 g/mol | C17H20ClNO4 | 1 ML

Amotosalen hydrochloride is a light-activated psoralen compound that crosslinks DNA and RNA upon UVA exposure, used for pathogen inactivation studies and for research applications requiring covalent nucleic acid modification. Supplied as a 10 mM solution (1 mL) with high purity and documented handling information, it is intended for laboratory research use under appropriate safety protocols.

Photoactivated crosslinking of DNA and RNA for pathogen inactivation studies.
Supplied as a ready-to-use 10 mM solution for consistent dosing.
High purity suitable for analytical and biological research applications.
Well-characterized molecular properties for reproducible results.
Includes SDS and datasheet documentation for safe handling and use.

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4,930

Medchemexpress LLC BMY-25368 hydrochloride | 86134-36-3 | 97.0% | 379.88 | 5 MG

BMY-25368 (SKF 94482) is a histamine H2 receptor antagonist that acts as a gastric acid secretion inhibitor. It competitively antagonizes gastric secretion stimulated by histamine, Pentagastrin, Bethanechol, and food. This product is for research use only and not intended for medical applications.

Acts as a histamine H2 receptor antagonist
Inhibits gastric acid secretion
Antagonizes gastric secretion stimulated by histamine, Pentagastrin, Bethanechol, and food
Light yellow to yellow solid
Suitable for laboratory research

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4,931

Medchemexpress LLC AkaLumine hydrochloride | 2558205-28-8 | 99.92% | 338.85 | 50 MG

AkaLumine hydrochloride is a D-luciferin analogue with a Km of 2.06 μM for recombinant firefly luciferase (Fluc) protein. It emits near-infrared (NIR) light (λmax=677 nm) in reactions with native Fluc. This allows for high tissue-penetration and increased detection sensitivity from deep-tissue targets.

D-luciferin analogue.
Emits near-infrared (NIR) light (λmax=677 nm) with native Fluc.
High tissue-penetration.
Increases detection sensitivity from deep-tissue targets.
Can be used to detect Akaluc expression in vitro.

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4,932

Medchemexpress LLC AkaLumine hydrochloride | 2558205-28-8 | 99.9% | 338.85 | 100 MG

AkaLumine hydrochloride is a D-luciferin analogue that emits near-infrared (NIR) light (λmax=677 nm) in reactions with native firefly luciferase (Fluc). This analogue provides high tissue-penetration and increases detection sensitivity from deep-tissue targets.

D-luciferin analogue
Emits near-infrared (NIR) light
High tissue-penetration
Increases detection sensitivity from deep-tissue targets
For research use only

Pricing & Availability

4,933

Medchemexpress LLC GB111-NH2 hydrochloride | 99.26% | 610.14 | 1 ML

GB111-NH2 hydrochloride is a cysteine cathepsin inhibitor, which can be used for cancer study. It is for research use only and not sold to patients.

Purity: 99.26%
Molecular weight: 610.14
Formula: C33H40ClN3O6
Appearance: Solid
Color: White to off-white
Storage: -20°C, sealed storage, away from moisture and light. In solvent: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light).
Solubility (in vitro): DMSO: 125 mg/mL (204.87 mM; needs ultrasonic; hygroscopic DMSO has a significant impact on solubility, use newly opened DMSO).
Related classifications: Metabolic enzyme/protease, cathepsin.

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4,934

Medchemexpress LLC SKF-34288 hydrochloride | 320386-54-7 | 98.6% | 10 MM * 1 ML

SKF-34288 (3-Mercaptopicolinic acid) hydrochloride is an orally active phosphoenolpyruvate carboxykinase (PEPCK) inhibitor with a Ki of 2-9 μM. It acts as a potent hypoglycemic agent by inhibiting glucose synthesis. Additionally, it inhibits Asn metabolism and leads to an increase in amino acids and amides. It is intended for research use only.

Potent phosphoenolpyruvate carboxykinase (PEPCK) inhibitor
Inhibits glucose synthesis
Increases amino acids and amides by inhibiting Asn metabolism
Inhibits C2C12 cell proliferation
Induces myogenic differentiation of C2C12 cells
Reduces mRNA expression of Pck2 and genes associated with serine biosynthesis
Reduces blood glucose in starved rats
Neutralizes Salbutamol-mediated hyperglycaemia in rabbits
Reduces pyruvate-induced blood glucose level in rats

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4,935

Medchemexpress LLC Voreloxin Hydrochloride | 175519-16-1 | 99.6% | 437.90 | 100 MG

Voreloxin Hydrochloride is a first-in-class topoisomerase II inhibitor that intercalates DNA and induces site-selective DNA DSB, G2 arrest, and apoptosis.

A first-in-class topoisomerase II poison and inhibitor that intercalates DNA and induces site-selective DNA DSB, G2 arrest, and apoptosis.
Inhibits topoisomerase II activity and induces site-selective DNA DSB.
Induces G2 arrest partially through topoisomerase II.
Cytotoxic activity requires DNA intercalation.
Demonstrates potent cytotoxic activity in AML cell lines.
Causes accumulation of cells in the S and G2 phases of the cell cycle and acts on topoisomerase II.

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Alcohols and polyols

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Medchemexpress LLC Pociredir hydrochloride | 2490676-19-0 | 99.9% | 439.87 | 5 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC IACS-9571 hydrochloride | 2319611-93-1 | 98.3% | 679.22 | 1 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Emixustat hydrochloride | 1141934-97-5 | 99.29% | 299.84 | 5 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC SCH-23390 hydrochloride | 125941-87-9 | 99.8% | 324.24 | 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC VU0453379 (hydrochloride) | 99.0% | 471.03 | 10 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Ru-ski 43 hydrochloride | 1782573-67-4 | 98.8% | 423.01 | 50 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC 4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide hydrochloride | 2115897-23-7 | MFCD32062443 | 99.2% | 467.02 | C22H31ClN4O3S | 10MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Yonkenafil hydrochloride | 804519-64-0 | 99.4% | 524.08 g/mol | C24H34ClN5O4S | 50MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Amotosalen hydrochloride | 161262-45-9 | MFCD09970539 | 99.9% | 337.8 g/mol | C17H20ClNO4 | 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC BMY-25368 hydrochloride | 86134-36-3 | 97.0% | 379.88 | 5 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC AkaLumine hydrochloride | 2558205-28-8 | 99.92% | 338.85 | 50 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC AkaLumine hydrochloride | 2558205-28-8 | 99.9% | 338.85 | 100 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC GB111-NH2 hydrochloride | 99.26% | 610.14 | 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC SKF-34288 hydrochloride | 320386-54-7 | 98.6% | 10 MM * 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Voreloxin Hydrochloride | 175519-16-1 | 99.6% | 437.90 | 100 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More